Benefits and opportunities of the transgenic Oncopig cancer model

Kirtan Joshi, Bhanu P. Telugu, Randall S. Prather, Jeffrey N. Bryan, Timothy J. Hoffman, Jussuf T. Kaifi, Satyanarayana Rachagani

Research output: Contribution to journalShort surveypeer-review


Cancer remains a leading cause of morbidity and mortality, and a paradigm shift is needed to fundamentally revisit drug development efforts. Pigs share close similarities to humans and may serve as an alternative model. Recently, a transgenic ‘Oncopig’ line has been generated to induce solid tumors with organ specificity, opening the potential of Oncopigs as a platform for developing novel therapeutic regimens.

Original languageEnglish (US)
Pages (from-to)182-184
Number of pages3
JournalTrends in Cancer
Issue number3
StatePublished - Mar 2024


  • Oncopig
  • large animal cancer model
  • porcine cancer model
  • transgenic cancer model
  • translational cancer research

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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