Benign squamous cells with pleomorphic microvilli in urine or bladder washings

T. Suzuki, M. St. John, S. M. Cohen, G. H. Friedell

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Exfoliated cells in catheterized urine or bladder washings from 49 patients were observed by light microscopy (LM) and by scanning electron microscopy (SEM). The specimens from seven of these patients (six postmenopausal females and one 85-year-old male) contained squamous cells with pleomorphic microvilli (PMV) on their surfaces. Four of these cases had no bladder lesions by cytoscopic examination. Three patients had recurrent papillary transitional-cell carcinoma of the bladder, and the cytologic specimens from two of then contained transitional cells with PMV. The distinction between squamous and transitional cell is readily made by SEM, based primarily on cell shape and thickness. The presence of PMV on otherwise-benign-appearing squamous cells in urine or bladder washing specimens may be a source of confusion in the interpretation of SEM findings. The presence of PMV on exfoliated squamous cells in cytologic material from the human urinary tract does not seem to have the same diagnostic and prognostic significance as the presence of PMV on transitional cells.

Original languageEnglish (US)
Pages (from-to)497-499
Number of pages3
JournalActa Cytologica
Volume27
Issue number5
StatePublished - 1983

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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    Suzuki, T., St. John, M., Cohen, S. M., & Friedell, G. H. (1983). Benign squamous cells with pleomorphic microvilli in urine or bladder washings. Acta Cytologica, 27(5), 497-499.