Bioinformatics databases and tools on dietary MicroRNA

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Empowered by the emerging genomics technology, there has been an increasingly large accumulation of noncoding RNA information, particularly on micro- RNAs in animals and plants. Research interest in microRNAs originating from food mostly focused on their bioavailability and cross-species transportation and regulation has recently grown due to the potential implication of regulatory role and cofounding impact in human health. This chapter reviews publicly available repositories and bioinformatics tools developed for dietary microRNA research, including the first dietary microRNA database (DMD) that archives microRNA sequence and annotation in various dietary sources, a new small RNA sequencing analytical pipeline focusing on the detection of both endogenous and exogenous microRNAs, and other general computational resources and tools for microRNA target prediction and functional analysis.

Original languageEnglish (US)
Title of host publicationHandbook of Nutrition, Diet, and Epigenetics
PublisherSpringer International Publishing
Pages2219-2232
Number of pages14
Volume3
ISBN (Electronic)9783319555300
ISBN (Print)9783319555294
DOIs
StatePublished - Jan 5 2019

Keywords

  • Bioinformatics
  • Dietary microRNA
  • Dietary microRNA database (DMD)
  • Exogenous microRNA
  • Exosome
  • Gene regulation network
  • Sequence motif
  • Small RNA sequencing
  • microRNA function
  • microRNA target prediction
  • microRNA transportation

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Cui, J. (2019). Bioinformatics databases and tools on dietary MicroRNA. In Handbook of Nutrition, Diet, and Epigenetics (Vol. 3, pp. 2219-2232). Springer International Publishing. https://doi.org/10.1007/978-3-319-55530-0_90