Abstract
Multistable proteins are defined as those that have available more than one most stable conformation. This capability requires a reversal of the most stable and metastable designations dependent upon environmental conditions. The concept of multistability is discussed with regard to enzyme maturation, hybrid vigor, metabolic temperature compensation, developmental gradients, membrane transport and the classical theory of allostery.
Original language | English (US) |
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Pages (from-to) | 507-515 |
Number of pages | 9 |
Journal | Journal of Theoretical Biology |
Volume | 40 |
Issue number | 3 |
DOIs | |
State | Published - Aug 22 1973 |
Externally published | Yes |
ASJC Scopus subject areas
- Statistics and Probability
- Modeling and Simulation
- Biochemistry, Genetics and Molecular Biology(all)
- Immunology and Microbiology(all)
- Agricultural and Biological Sciences(all)
- Applied Mathematics