TY - BOOK
T1 - Biology and pathogenesis of rhabdo- and filoviruses
AU - Pattnaik, Asit K.
AU - Whitt, Michael A.
N1 - Publisher Copyright:
© 2015 by World Scientific Publishing Co. Pte. Ltd. All rights reserved.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Rhabdoviruses and Filoviruses are single-stranded, non-segmented, negative-strand RNA viruses, many of which cause significant morbidity and mortality in humans and animals. Certain members of these virus families have been used as excellent model systems to understand the molecular biology of replication, host responses to infections, and viral countermeasures. Rhabdoviruses have also been used as vaccine vectors as well as oncolytic agents. Studies on Filoviruses have now provided significant insights into how they enter susceptible cells, replicate and cause disease, and also how they evade the host’s immune mechanisms. This book addresses the most recent findings on Rhabdovirus and Filovirus structure, replication mechanisms, host cell responses to virus infections and viral countermeasures. Chapters on emerging viruses as well as approaches for therapeutic interventions have also been included. This book represents an authoritative text that brings together the most recent advances on the cellular and molecular biology of Rhabdo- and Filoviruses, including mechanisms of pathogenesis.
AB - Rhabdoviruses and Filoviruses are single-stranded, non-segmented, negative-strand RNA viruses, many of which cause significant morbidity and mortality in humans and animals. Certain members of these virus families have been used as excellent model systems to understand the molecular biology of replication, host responses to infections, and viral countermeasures. Rhabdoviruses have also been used as vaccine vectors as well as oncolytic agents. Studies on Filoviruses have now provided significant insights into how they enter susceptible cells, replicate and cause disease, and also how they evade the host’s immune mechanisms. This book addresses the most recent findings on Rhabdovirus and Filovirus structure, replication mechanisms, host cell responses to virus infections and viral countermeasures. Chapters on emerging viruses as well as approaches for therapeutic interventions have also been included. This book represents an authoritative text that brings together the most recent advances on the cellular and molecular biology of Rhabdo- and Filoviruses, including mechanisms of pathogenesis.
UR - http://www.scopus.com/inward/record.url?scp=84988598781&partnerID=8YFLogxK
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U2 - 10.1142/P9394
DO - 10.1142/P9394
M3 - Book
AN - SCOPUS:84988598781
SN - 9789814635332
BT - Biology and pathogenesis of rhabdo- and filoviruses
PB - World Scientific Publishing Co.
ER -