Biomarkers for neuroAIDS: The widening scope of metabolomics

Gurudutt Pendyala, Elizabeth J. Want, William Webb, Gary Siuzdak, Howard S. Fox

Research output: Contribution to journalReview articlepeer-review

29 Scopus citations


"Metabolomics", the measurement of metabolite concentrations and fluxes in cell systems, is an emerging science that has enormous potential and several unique characteristics. The current applications for this field are, primarily, toxicological profiling and biomarker studies. This review of metabolomics research highlights the identification of reliable biomarkers with emphasis on neuroAIDS. Such identification of candidate markers will be advantageous for tracking the progression of human immunodeficiency virus/central nervous system (HIV/CNS) disease to gain maximal benefit from antiretroviral treatment and to provide insight into the mechanism of related neuropathogenesis.

Original languageEnglish (US)
Pages (from-to)72-80
Number of pages9
JournalJournal of Neuroimmune Pharmacology
Issue number1
StatePublished - Mar 2007
Externally publishedYes


  • Biomarkers
  • CNS
  • HIV
  • Mass spectrometry
  • Metabolomics
  • NeuroAIDS
  • SIV

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Immunology and Allergy
  • Immunology
  • Pharmacology


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