Biomarkers for neuroAIDS: The widening scope of metabolomics

Gurudutt Pendyala, Elizabeth J. Want, William Webb, Gary Siuzdak, Howard S. Fox

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations

Abstract

"Metabolomics", the measurement of metabolite concentrations and fluxes in cell systems, is an emerging science that has enormous potential and several unique characteristics. The current applications for this field are, primarily, toxicological profiling and biomarker studies. This review of metabolomics research highlights the identification of reliable biomarkers with emphasis on neuroAIDS. Such identification of candidate markers will be advantageous for tracking the progression of human immunodeficiency virus/central nervous system (HIV/CNS) disease to gain maximal benefit from antiretroviral treatment and to provide insight into the mechanism of related neuropathogenesis.

Original languageEnglish (US)
Pages (from-to)72-80
Number of pages9
JournalJournal of Neuroimmune Pharmacology
Volume2
Issue number1
DOIs
StatePublished - Mar 2007

Keywords

  • Biomarkers
  • CNS
  • HIV
  • Mass spectrometry
  • Metabolomics
  • NeuroAIDS
  • SIV

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Immunology and Allergy
  • Immunology
  • Pharmacology

Fingerprint Dive into the research topics of 'Biomarkers for neuroAIDS: The widening scope of metabolomics'. Together they form a unique fingerprint.

Cite this