Biomechanical evaluation of in-stenting restenosis

Linxia Gu, Aswini K. Muttyam

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Coronary heart disease is the single leading cause of death in America today. Annually, an estimated 1.2 million Americans suffer from a new or recurrent coronary attack. Coronary heart disease is caused by atherosclerosis, the narrowing of the coronary arteries due to fatty build ups of plaque. It's likely to produce angina pectoris (chest pain), heart attack or both. The placement of a stent in the artery is used to prevent the collapse of the balloon treated artery. However the struts can introduce the excessive stresses on the artery wall and cause the artery to be re-blocked after weeks or months (instent restenosis). This study will quantify how key parameters of a stent such as mesh design, strut thickness, and plaque geometry affect the restenosis conditions. Results will identify the desirable properties necessary for the development of effective therapeutic strategy for reducing in-stent restenosis.

Original languageEnglish (US)
Title of host publicationBiomedical and Biotechnology Engineering
PublisherAmerican Society of Mechanical Engineers (ASME)
Number of pages4
ISBN (Electronic)0791842967
StatePublished - 2007
Externally publishedYes
EventASME 2007 International Mechanical Engineering Congress and Exposition, IMECE 2007 - Seattle, United States
Duration: Nov 11 2007Nov 15 2007

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)


OtherASME 2007 International Mechanical Engineering Congress and Exposition, IMECE 2007
Country/TerritoryUnited States

ASJC Scopus subject areas

  • Mechanical Engineering
  • Engineering(all)


Dive into the research topics of 'Biomechanical evaluation of in-stenting restenosis'. Together they form a unique fingerprint.

Cite this