Biomechanical evaluation of in-stenting restenosis

Linxia Gu, Aswini K. Muttyam

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Coronary heart disease is the single leading cause of death in America today. Annually, an estimated 1.2 million Americans suffer from a new or recurrent coronary attack. Coronary heart disease is caused by atherosclerosis, the narrowing of the coronary arteries due to fatty build ups of plaque. It's likely to produce angina pectoris (chest pain), heart attack or both. The placement of a stent in the artery is used to prevent the collapse of the balloon treated artery. However the struts can introduce the excessive stresses on the artery wall and cause the artery to be re-blocked after weeks or months (instent restenosis). This study will quantify how key parameters of a stent such as mesh design, strut thickness, and plaque geometry affect the restenosis conditions. Results will identify the desirable properties necessary for the development of effective therapeutic strategy for reducing in-stent restenosis.

Original languageEnglish (US)
Title of host publicationBiomedical and Biotechnology Engineering
PublisherAmerican Society of Mechanical Engineers (ASME)
Pages187-190
Number of pages4
ISBN (Electronic)0791842967
DOIs
StatePublished - Jan 1 2007
EventASME 2007 International Mechanical Engineering Congress and Exposition, IMECE 2007 - Seattle, United States
Duration: Nov 11 2007Nov 15 2007

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume2

Other

OtherASME 2007 International Mechanical Engineering Congress and Exposition, IMECE 2007
CountryUnited States
CitySeattle
Period11/11/0711/15/07

ASJC Scopus subject areas

  • Mechanical Engineering
  • Engineering(all)

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  • Cite this

    Gu, L., & Muttyam, A. K. (2007). Biomechanical evaluation of in-stenting restenosis. In Biomedical and Biotechnology Engineering (pp. 187-190). (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 2). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/IMECE2007-41280