Bioprinting of cardiac tissues

Daniel Y.C. Cheung, Bin Duan, Jonathan T. Butcher

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Abstract

Cardiovascular disease remains the leading cause of death in the world. Cardiac and heart valve tissue engineering in the past decade have made progress to recapitulate the native properties of the heart for cardiac regeneration and repair using a myriad of strategies, including concepts of biomaterials, micro-and nanotechnologies, and decellularization. However, one main obstacle for tissue engineering cardiac tissue is incorporating the complex, heterogeneous micro-and macro-cardiac tissue structures for different cell types to adhere, proliferate, and ultimately repair and remodel damaged tissue. 3D bioprinting has emerged as a strategy to address this challenge by providing the technology to fabricate high-resolution scaffolds with heterogeneous biochemical and mechanical properties. This chapter gives an overview of current strategies and limitations for cardiac and heart valve tissue engineering and the advances made in 3D bioprinting for cardiac repair.

Original languageEnglish (US)
Title of host publicationEssentials of 3D Biofabrication and Translation
PublisherElsevier Inc.
Pages351-370
Number of pages20
ISBN (Electronic)9780128010150
ISBN (Print)9780128009727
DOIs
StatePublished - Aug 7 2015

Keywords

  • 3D printing
  • Bioreactor
  • Heart valve
  • Microfabrication
  • Tissue engineering

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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    Cheung, D. Y. C., Duan, B., & Butcher, J. T. (2015). Bioprinting of cardiac tissues. In Essentials of 3D Biofabrication and Translation (pp. 351-370). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-800972-7.00021-9