Biosocial processes predicting multisystemic therapy treatment response

Stacy R. Ryan; Patricia A. Brennan; Phillippe B. Cunningham; Sharon L. Foster; Rebecca L. Brock; Elizabeth Whitmore

doi:10.1016/j.biopsycho.2012.12.002

Biosocial processes predicting multisystemic therapy treatment response

Stacy R. Ryan, Patricia A. Brennan, Phillippe B. Cunningham, Sharon L. Foster, Rebecca L. Brock, Elizabeth Whitmore

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

This study examined biological (testosterone) and social (deviant peer affiliation) factors early in treatment as predictors of treatment outcome among adolescent boys receiving Multisystemic Therapy (MST) in community settings. Outcome variables included changes in youth aggression and delinquency as reported by the primary caregiver. Testosterone and deviant peer affiliation were assessed at treatment onset; and outcome variables (aggression and delinquency) were assessed at treatment onset, mid-treatment and end-of-treatment. Participants were 112 adolescent boys (M age = 15.42, SD=1.31) and their caregivers. Growth curve analyses revealed that the combination of high testosterone and high deviant peer affiliation early in treatment were significantly associated with less of a decline in aggression and delinquency over the course of treatment. Results provide novel evidence for the role of testosterone in the prediction of future externalizing behaviors. Clinical and theoretical implications are discussed.

Original language	English (US)
Pages (from-to)	373-379
Number of pages	7
Journal	Biological Psychology
Volume	92
Issue number	2
DOIs	https://doi.org/10.1016/j.biopsycho.2012.12.002
State	Published - Feb 2013
Externally published	Yes

Keywords

Aggression
Deviant peers
MST
Testosterone
Treatment outcome

ASJC Scopus subject areas

Neuroscience(all)
Neuropsychology and Physiological Psychology

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10.1016/j.biopsycho.2012.12.002

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title = "Biosocial processes predicting multisystemic therapy treatment response",

abstract = "This study examined biological (testosterone) and social (deviant peer affiliation) factors early in treatment as predictors of treatment outcome among adolescent boys receiving Multisystemic Therapy (MST) in community settings. Outcome variables included changes in youth aggression and delinquency as reported by the primary caregiver. Testosterone and deviant peer affiliation were assessed at treatment onset; and outcome variables (aggression and delinquency) were assessed at treatment onset, mid-treatment and end-of-treatment. Participants were 112 adolescent boys (M age = 15.42, SD=1.31) and their caregivers. Growth curve analyses revealed that the combination of high testosterone and high deviant peer affiliation early in treatment were significantly associated with less of a decline in aggression and delinquency over the course of treatment. Results provide novel evidence for the role of testosterone in the prediction of future externalizing behaviors. Clinical and theoretical implications are discussed.",

keywords = "Aggression, Deviant peers, MST, Testosterone, Treatment outcome",

author = "Ryan, {Stacy R.} and Brennan, {Patricia A.} and Cunningham, {Phillippe B.} and Foster, {Sharon L.} and Brock, {Rebecca L.} and Elizabeth Whitmore",

note = "Funding Information: Results decribed in this article were included in Stacy Ryan's doctoral dissertation. In addition, prliminary results described in this article were previously presented at the Biennial Meeting of the Society for Research in Child Development, Denver, Colorado, April 2009. This project was supported by Grant R01 MH068813 and by supplement grant R01 MH068813-03S1 from the National Institute of Mental Health . We thank the families that participated in this project as well as the clinical and research teams and lead research coordinator, Angie Wold. ",

year = "2013",

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doi = "10.1016/j.biopsycho.2012.12.002",

language = "English (US)",

volume = "92",

pages = "373--379",

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AU - Ryan, Stacy R.

AU - Brennan, Patricia A.

AU - Cunningham, Phillippe B.

AU - Foster, Sharon L.

AU - Brock, Rebecca L.

AU - Whitmore, Elizabeth

N1 - Funding Information: Results decribed in this article were included in Stacy Ryan's doctoral dissertation. In addition, prliminary results described in this article were previously presented at the Biennial Meeting of the Society for Research in Child Development, Denver, Colorado, April 2009. This project was supported by Grant R01 MH068813 and by supplement grant R01 MH068813-03S1 from the National Institute of Mental Health . We thank the families that participated in this project as well as the clinical and research teams and lead research coordinator, Angie Wold.

PY - 2013/2

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N2 - This study examined biological (testosterone) and social (deviant peer affiliation) factors early in treatment as predictors of treatment outcome among adolescent boys receiving Multisystemic Therapy (MST) in community settings. Outcome variables included changes in youth aggression and delinquency as reported by the primary caregiver. Testosterone and deviant peer affiliation were assessed at treatment onset; and outcome variables (aggression and delinquency) were assessed at treatment onset, mid-treatment and end-of-treatment. Participants were 112 adolescent boys (M age = 15.42, SD=1.31) and their caregivers. Growth curve analyses revealed that the combination of high testosterone and high deviant peer affiliation early in treatment were significantly associated with less of a decline in aggression and delinquency over the course of treatment. Results provide novel evidence for the role of testosterone in the prediction of future externalizing behaviors. Clinical and theoretical implications are discussed.

AB - This study examined biological (testosterone) and social (deviant peer affiliation) factors early in treatment as predictors of treatment outcome among adolescent boys receiving Multisystemic Therapy (MST) in community settings. Outcome variables included changes in youth aggression and delinquency as reported by the primary caregiver. Testosterone and deviant peer affiliation were assessed at treatment onset; and outcome variables (aggression and delinquency) were assessed at treatment onset, mid-treatment and end-of-treatment. Participants were 112 adolescent boys (M age = 15.42, SD=1.31) and their caregivers. Growth curve analyses revealed that the combination of high testosterone and high deviant peer affiliation early in treatment were significantly associated with less of a decline in aggression and delinquency over the course of treatment. Results provide novel evidence for the role of testosterone in the prediction of future externalizing behaviors. Clinical and theoretical implications are discussed.

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Biosocial processes predicting multisystemic therapy treatment response

Abstract

Keywords

ASJC Scopus subject areas

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