Abstract
Bone marrow necrosis is a rare and ominous complication of hematologic malignancy which is often associated with bone pain in the lower back and extremities. Widespread marrow necrosis makes a definitive diagnosis through bone marrow biopsy difficult. An accurate diagnosis is imperative in patients with promyelocytic leukemia (FAB-M3) because disseminated intravascular coagulation and hemorrhage secondary to release of tissue thromboplastins from the malignant cell population requires prompt and anticipatory therapy. The following case report describes a patient wkth acute leukemia and massive bone marrow necrosis which obscured the correct diagnosis of promyelocytic leukemia.
Original language | English (US) |
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Pages (from-to) | 51-54 |
Number of pages | 4 |
Journal | Hematologic Pathology |
Volume | 2 |
Issue number | 1 |
State | Published - 1988 |
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Hematology