Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

S. J. Forman; M. R. O'Donnell; A. P. Nademanee; D. S. Snyder; P. J. Bierman; G. M. Schmidt; J. L. Fahey; A. S. Stein; P. M. Parker; K. G. Blume

doi:10.1182/blood.v70.2.587.bloodjournal702587

Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

S. J. Forman, M. R. O'Donnell, A. P. Nademanee, D. S. Snyder, P. J. Bierman, G. M. Schmidt, J. L. Fahey, A. S. Stein, P. M. Parker, K. G. Blume

Research output: Contribution to journal › Article › peer-review

89 Scopus citations

Abstract

We report the treatment outcome of allogeneic bone marrow transplantation in ten patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Six patients are alive and well for 6 to 30 months (median 19 months) after transplantation. Four patients died with transplant related complications. In view of the poor prognosis associated with this disease, marrow ablation followed by allogeneic or syngeneic marrow grafting may be the preferred treatment modality if a suitable marrow donor is available.

Original language	English (US)
Pages (from-to)	587-588
Number of pages	2
Journal	Blood
Volume	70
Issue number	2
DOIs	https://doi.org/10.1182/blood.v70.2.587.bloodjournal702587
State	Published - Aug 1 1987
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Immunology
Hematology
Cell Biology

Access to Document

10.1182/blood.v70.2.587.bloodjournal702587

Cite this

@article{ae47c60993354941b8e4a0c17c1784d1,

title = "Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia",

abstract = "We report the treatment outcome of allogeneic bone marrow transplantation in ten patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Six patients are alive and well for 6 to 30 months (median 19 months) after transplantation. Four patients died with transplant related complications. In view of the poor prognosis associated with this disease, marrow ablation followed by allogeneic or syngeneic marrow grafting may be the preferred treatment modality if a suitable marrow donor is available.",

author = "Forman, {S. J.} and O'Donnell, {M. R.} and Nademanee, {A. P.} and Snyder, {D. S.} and Bierman, {P. J.} and Schmidt, {G. M.} and Fahey, {J. L.} and Stein, {A. S.} and Parker, {P. M.} and Blume, {K. G.}",

year = "1987",

month = aug,

day = "1",

doi = "10.1182/blood.v70.2.587.bloodjournal702587",

language = "English (US)",

volume = "70",

pages = "587--588",

journal = "Blood",

issn = "0006-4971",

publisher = "Elsevier B.V.",

number = "2",

}

TY - JOUR

T1 - Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

AU - Forman, S. J.

AU - O'Donnell, M. R.

AU - Nademanee, A. P.

AU - Snyder, D. S.

AU - Bierman, P. J.

AU - Schmidt, G. M.

AU - Fahey, J. L.

AU - Stein, A. S.

AU - Parker, P. M.

AU - Blume, K. G.

PY - 1987/8/1

Y1 - 1987/8/1

N2 - We report the treatment outcome of allogeneic bone marrow transplantation in ten patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Six patients are alive and well for 6 to 30 months (median 19 months) after transplantation. Four patients died with transplant related complications. In view of the poor prognosis associated with this disease, marrow ablation followed by allogeneic or syngeneic marrow grafting may be the preferred treatment modality if a suitable marrow donor is available.

AB - We report the treatment outcome of allogeneic bone marrow transplantation in ten patients with Philadelphia chromosome-positive acute lymphoblastic leukemia. Six patients are alive and well for 6 to 30 months (median 19 months) after transplantation. Four patients died with transplant related complications. In view of the poor prognosis associated with this disease, marrow ablation followed by allogeneic or syngeneic marrow grafting may be the preferred treatment modality if a suitable marrow donor is available.

UR - http://www.scopus.com/inward/record.url?scp=0023201015&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023201015&partnerID=8YFLogxK

U2 - 10.1182/blood.v70.2.587.bloodjournal702587

DO - 10.1182/blood.v70.2.587.bloodjournal702587

M3 - Article

C2 - 3300815

AN - SCOPUS:0023201015

SN - 0006-4971

VL - 70

SP - 587

EP - 588

JO - Blood

JF - Blood

IS - 2

ER -

Bone marrow transplantation for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this