Ca(II)-calmodulin regulation of morphological commitment in Ceratocystis ulmi

Ganapathy Muthukumar, Kenneth W. Nickerson

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The commitment phenomenon exhibited by Ceratocystis ulmi is a manifestation of the requirement for a Ca(II)-calmodulin interaction for mycelial growth. Under otherwise identical conditions, addition of CaCl2(10 mM) to committed yeasts caused them to germinate, while addition of the calmodulin antagonists chlorpromazine (80 μM), dibucaine (750 μM), or trifluoperazine (60 μM) to committed mycelia caused them to bud.

Original languageEnglish (US)
Pages (from-to)199-202
Number of pages4
JournalFEMS Microbiology Letters
Issue number2
StatePublished - May 1985
Externally publishedYes


  • Fungal dimorphism
  • cell shape
  • chlorpromazine
  • refractile lipid bodies

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology
  • Genetics


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