Cap-binding complex protein p220 is not cleaved during echovirus 22 replication in HeLa cells

B. A.G. Coller; S. M. Tracy; D. Etchison

doi:10.1128/jvi.65.7.3903-3905.1991

Cap-binding complex protein p220 is not cleaved during echovirus 22 replication in HeLa cells

B. A.G. Coller, S. M. Tracy, D. Etchison

Research output: Contribution to journal › Comment/debate › peer-review

19 Scopus citations

Abstract

Previously we demonstrated that echovirus 22 is an atypical enterovirus which does not shut off host cell protein synthesis. We extend these findings by showing that echovirus 22 does not cleave p220, part of the cellular cap-binding complex necessary for cap-dependent translation, suggesting a biology more consistent with cardioviruses than enteroviruses.

Original language	English (US)
Pages (from-to)	3903-3905
Number of pages	3
Journal	Journal of virology
Volume	65
Issue number	7
DOIs	https://doi.org/10.1128/jvi.65.7.3903-3905.1991
State	Published - 1991
Externally published	Yes

ASJC Scopus subject areas

Microbiology
Immunology
Insect Science
Virology

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10.1128/jvi.65.7.3903-3905.1991

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title = "Cap-binding complex protein p220 is not cleaved during echovirus 22 replication in HeLa cells",

abstract = "Previously we demonstrated that echovirus 22 is an atypical enterovirus which does not shut off host cell protein synthesis. We extend these findings by showing that echovirus 22 does not cleave p220, part of the cellular cap-binding complex necessary for cap-dependent translation, suggesting a biology more consistent with cardioviruses than enteroviruses.",

author = "Coller, {B. A.G.} and Tracy, {S. M.} and D. Etchison",

year = "1991",

doi = "10.1128/jvi.65.7.3903-3905.1991",

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T1 - Cap-binding complex protein p220 is not cleaved during echovirus 22 replication in HeLa cells

AU - Coller, B. A.G.

AU - Tracy, S. M.

AU - Etchison, D.

PY - 1991

Y1 - 1991

N2 - Previously we demonstrated that echovirus 22 is an atypical enterovirus which does not shut off host cell protein synthesis. We extend these findings by showing that echovirus 22 does not cleave p220, part of the cellular cap-binding complex necessary for cap-dependent translation, suggesting a biology more consistent with cardioviruses than enteroviruses.

AB - Previously we demonstrated that echovirus 22 is an atypical enterovirus which does not shut off host cell protein synthesis. We extend these findings by showing that echovirus 22 does not cleave p220, part of the cellular cap-binding complex necessary for cap-dependent translation, suggesting a biology more consistent with cardioviruses than enteroviruses.

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U2 - 10.1128/jvi.65.7.3903-3905.1991

DO - 10.1128/jvi.65.7.3903-3905.1991

M3 - Comment/debate

C2 - 2041099

AN - SCOPUS:0025879384

SN - 0022-538X

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EP - 3905

JO - Journal of virology

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IS - 7

ER -

Cap-binding complex protein p220 is not cleaved during echovirus 22 replication in HeLa cells

Abstract

ASJC Scopus subject areas

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