Carcinogenicity of the antineoplastic agent, 5 (3,3 dimethyl 1 triazeno) imidazole 4 carboxamide, and its metabolites in rats

Medicine & Life Sciences

• imidazole-4-carboxamide 100%
• Dacarbazine 71%
• Antineoplastic Agents 53%
• Adenofibroma 35%
• Breast 26%
• Incidence 23%
• Thymus Neoplasms 20%
• Leiomyosarcoma 16%
• Adenocarcinoma 16%
• 5-diazoimidazole-4-carboxamide 15%
• 2-azahypoxanthine 15%
• 5-(3-methyl-1-triazeno)imidazole-4-carboxamide 14%
• Intraperitoneal Injections 13%
• Breast Neoplasms 13%
• Aminoimidazole Carboxamide 11%
• 4-aminoimidazole 10%
• Nitroso Compounds 10%
• Alkanes 10%
• hydrazine 10%
• Primitive Neuroectodermal Tumors 9%
• Buffaloes 9%
• Organ Specificity 8%
• Tissue Distribution 7%
• Neoplasms 6%
• Urinary Bladder Neoplasms 6%
• Non-Hodgkin's Lymphoma 6%
• Oral Administration 6%
• Stomach 5%
• Animals 3%