Carcinoid crisis and reversible right ventricular dysfunction after embolization in untreated carcinoid syndrome

Farhan Majeed, Thomas R. Porter, Stefano Tarantolo, Amy Duhachek-Stapelman, Feng Xie, Abdou Elhendy

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

A 59-year-old white male with carcinoid tumor and hepatic metastases underwent hepatic artery embolization. The patient developed carcinoid crisis and a subsequent transthoracic echocardiogram showed classic findings of carcinoid heart disease along with a dilated hypertrophied right ventricle and severely depressed right ventricular ejection fraction. After treatment with octreotide the patient's clinical condition improved and a repeat transthoracic echocardiogram showed a significant improvement and normalization of right ventricular systolic function. Serotonin levels showed a progressive decline that correlated well with the patient's improved clinical condition. These findings suggest that the acute right ventricular dysfunction was secondary to acute carcinoid crisis and resolution resulted in a significant improvement of both right ventricular systolic function and clinical condition.

Original languageEnglish (US)
Pages (from-to)386-389
Number of pages4
JournalEuropean Journal of Echocardiography
Volume8
Issue number5
DOIs
StatePublished - Oct 2007

Keywords

  • Carcinoid crisis
  • Right ventricle
  • Serotonin

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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