Cardiac complications observed in elderly patients following 2′‐deoxycoformycin therapy

Jean L. Grem, Susan A. King, Hoo G. Chun, Michael R. Grever

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Deoxycoformycin (dCF) is an investigational nucleoside with significant activity in hairy cell leukemia, cutaneous T‐cell lymphoma, and chronic lymphocytic leukemia. During a 4‐year period, 11 patients have experienced cardiac events as a complication of dCF therapy under NCI sponsorship. The cases are presented and recommendations for the administration of dCF to patients with pre‐existing heart disease are made.

Original languageEnglish (US)
Pages (from-to)245-247
Number of pages3
JournalAmerican Journal of Hematology
Volume38
Issue number3
DOIs
StatePublished - Nov 1991

Keywords

  • 2′‐deoxycoformycin
  • cardiac side effects
  • pentostatin

ASJC Scopus subject areas

  • Hematology

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