@inbook{fc319987b3674feaad20e1475404844a,
title = "Cardiac wound healing post-myocardial infarction: A novel method to target extracellular matrix remodeling in the left ventricle",
abstract = "Myocardial infarction (MI) is a leading cause of death worldwide. Permanent ligation of the left anterior descending coronary artery (LAD) is a commonly used surgical model to study post-MI effects in mice. LAD occlusion induces a robust wound healing response that includes extracellular matrix (ECM) remodeling. This chapter provides a detailed guide on the surgical procedure to permanently ligate the LAD. Additionally, we describe a prototype method to enrich cardiac tissue for ECM, which allows one to focus on ECM remodeling in the left ventricle following surgically induced MI in mice.",
keywords = "Cardiac wound healing, Decellularization, Extracellular matrix, Inflammation, Matrix metalloproteinases, Mice, Myocardial infarction",
author = "Rogelio Zamilpa and Jianhua Zhang and Chiao, {Ying Ann} and {De Castro Br{\'a}s}, {Lisandra E.} and Halade, {Ganesh V.} and Yonggang Ma and Hacker, {Sander O.} and Lindsey, {Merry L.}",
year = "2013",
doi = "10.1007/978-1-62703-505-7_18",
language = "English (US)",
isbn = "9781627035040",
series = "Methods in Molecular Biology",
publisher = "Humana Press Inc.",
pages = "313--324",
booktitle = "Wound Regeneration and Repair",
}