Carotid endarterectomy ⇔ specific therapy based on pathophysiology

J. Philip Kistler, Ferdinando S. Buonanno, Daryl R. Gress

Research output: Contribution to journalEditorialpeer-review

26 Scopus citations


Atherosclerotic narrowing at the bifurcation of the common carotid artery is by far the most common cause of large-vessel atherothrombotic stroke. Atherosclerotic plaque tends to form in the posterior part of the bifurcation, at the origin of the internal carotid artery, narrowing the lumen until it resembles an hourglass whose tapered segment is usually 1 to 2 mm long. A mural thrombus may form at, or near, the residual lumen,1,2 which is usually located eccentrically in the anterior medial portion of the proximal internal carotid artery. Occasionally, blood from the lumen penetrates into the plaque. This penetration may be the.

Original languageEnglish (US)
Pages (from-to)505-507
Number of pages3
JournalNew England Journal of Medicine
Issue number7
StatePublished - Aug 15 1991
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)


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