Catalytic cobalt-mediated reductive carbocyclizations

James M. Takacs, Steven J. Mehrman

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The cobalt-catalyzed cyclization of certain acyclic enediene substrates proceeds stereoselectively to afford substituted divinyl cyclopentanes and cyclohexanes in good yield. A variation, involving a substrate wherein a suitably disposed alkyne separates the reacting alkene and 1,3-diene partners, affords a novel cascade cyclization product.

Original languageEnglish (US)
Pages (from-to)2749-2752
Number of pages4
JournalTetrahedron Letters
Volume37
Issue number16
DOIs
StatePublished - Apr 15 1996

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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