Central bump-like opacity as a complication of high hyperopic photorefractive keratectomy

Zoltán Zsolt Nagy, Ronald R. Krueger, Ildikó Süveges

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


PURPOSE: A new complication is reported in association with high hyperopic excimer laser photorefractive keratectomy. METHODS: One thousand consecutive eyes were treated with a Meditec MEL-60 excimer laser (Meditec Inc, Heroldsberg, Germany) for hyperopic refractive error between +1 diopters and +7 diopters. RESULTS: Three eyes with high hyperopic corrections between +5 and +6 diopters had a central, round bump-like subepithelial scar develop 1 month after hyperopic photorefractive keratectomy, which reduced the uncorrected and spectacle-corrected visual acuity. CONCLUSION: Central bump- like opacity is a new, visually significant complication of unknown origin associated with high hyperopic photorefractive keratectomy. Possible causes of this complication include drying and edema of the cornea as a result of prolonged exposure, interruption of the peripheral superficial nerve plexus affecting the central anterior stroma, and abnormal epithelial or tear film function resulting from excessive central steeping.

Original languageEnglish (US)
Pages (from-to)636-638
Number of pages3
JournalAmerican journal of ophthalmology
Issue number5
StatePublished - Nov 1999
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology


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