Cerebrospinal fluid transthyretin in the neonate and blood–cerebrospinal fluid barrier permeability

Paul D. Larsen; Leonard Delallo

doi:10.1002/ana.410250617

Cerebrospinal fluid transthyretin in the neonate and blood–cerebrospinal fluid barrier permeability

Paul D. Larsen, Leonard Delallo

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

We measured transthyretin levels in the cerebrospinal fluid (CSF) of newborn infants, older children, patients with viral and bacterial meningitis, and adults with increased CSF protein levels. Neonatal CSF transthyretin levels are elevated disproportionately in comparison to levels in the other groups. We conclude that increased levels of transthyretin in the CSF of neonates are not explained by increased permeability of the blood–CSF barrier.

Original language	English (US)
Pages (from-to)	628-630
Number of pages	3
Journal	Annals of Neurology
Volume	25
Issue number	6
DOIs	https://doi.org/10.1002/ana.410250617
State	Published - Jun 1989
Externally published	Yes

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1002/ana.410250617

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title = "Cerebrospinal fluid transthyretin in the neonate and blood–cerebrospinal fluid barrier permeability",

abstract = "We measured transthyretin levels in the cerebrospinal fluid (CSF) of newborn infants, older children, patients with viral and bacterial meningitis, and adults with increased CSF protein levels. Neonatal CSF transthyretin levels are elevated disproportionately in comparison to levels in the other groups. We conclude that increased levels of transthyretin in the CSF of neonates are not explained by increased permeability of the blood–CSF barrier.",

author = "Larsen, {Paul D.} and Leonard Delallo",

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AU - Larsen, Paul D.

AU - Delallo, Leonard

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AB - We measured transthyretin levels in the cerebrospinal fluid (CSF) of newborn infants, older children, patients with viral and bacterial meningitis, and adults with increased CSF protein levels. Neonatal CSF transthyretin levels are elevated disproportionately in comparison to levels in the other groups. We conclude that increased levels of transthyretin in the CSF of neonates are not explained by increased permeability of the blood–CSF barrier.

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Cerebrospinal fluid transthyretin in the neonate and blood–cerebrospinal fluid barrier permeability

Abstract

ASJC Scopus subject areas

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