Cerebrospinal fluid transthyretin in the neonate and blood–cerebrospinal fluid barrier permeability

Paul D. Larsen, Leonard Delallo

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

We measured transthyretin levels in the cerebrospinal fluid (CSF) of newborn infants, older children, patients with viral and bacterial meningitis, and adults with increased CSF protein levels. Neonatal CSF transthyretin levels are elevated disproportionately in comparison to levels in the other groups. We conclude that increased levels of transthyretin in the CSF of neonates are not explained by increased permeability of the blood–CSF barrier.

Original languageEnglish (US)
Pages (from-to)628-630
Number of pages3
JournalAnnals of Neurology
Volume25
Issue number6
DOIs
StatePublished - Jun 1989

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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