Cervical cancer control, priorities and new directions

Joseph Monsonego, F. Xavier Bosch, Pierre Coursaget, John Thomas Cox, Eduardo Franco, Ian Frazer, Rengaswamy Sankaranarayanan, John Schiller, Albert Singer, Tom Wright, Walter Kinney, Chris Meijer, James Linder

Research output: Contribution to journalShort surveypeer-review

110 Scopus citations


Cervical cancer is caused by infection with a range of high risk "oncogenic" human papillomavirus (HPV) types, and it is now accepted that >99% of cervical cancer is initiated by HPV infection. The estimated lifetime risk of cervical cancer is nevertheless relatively low (less than 1 in 20 for most community based studies). Although sensitivity and specificity of the available diagnostic techniques are suboptimal, screening for persistent HPV infection is effective in reducing the incidence of cervical cancer. Infection can be detected by molecular techniques or by cytological examination of exfoliated cervical cells. Persistent infection is the single best predictor of risk of cervical cancer. The latest findings of HPV and cervical cancer research need to be widely disseminated to the scientific and medical societies that are updating screening and management protocols, public health professionals, and to women and clinicians. This report reviews current evidence, clinical implications and directions for further research in the prevention, control and management of cervical cancer. We report the conclusions of the Experts' Meeting at the EUROGIN 2003 conference.

Original languageEnglish (US)
Pages (from-to)329-333
Number of pages5
JournalInternational Journal of Cancer
Issue number3
StatePublished - Jan 20 2004
Externally publishedYes


  • Cervical neoplasia
  • Colposcopy
  • HPV vaccine
  • Human papillomavirus
  • Screening

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


Dive into the research topics of 'Cervical cancer control, priorities and new directions'. Together they form a unique fingerprint.

Cite this