Osobennosti reguliatsii immunnogo otveta pri virusnykh gepatitakh A i B.

Translated title of the contribution: Characteristics of immune response regulation in viral hepatitis A and B

A. F. Bliuger, K. M. Veksler, N. A. Osna, R. G. Charnaia, I. N. Novitskiǐ

Research output: Contribution to journalArticle

Abstract

In 272 patients with virus hepatitis A and B the content of theophylline-sensitive lymphocytes (T-suppressors) and theophylline-resistant lymphocytes (T-helpers) in the peripheral blood was determined. Differences in the content of T-suppressors in cases of acute virus hepatitis A and B with an equal degree of severity were revealed: at the peak of hepatitis A infection in the mild form of the disease the number of the cells was decreased, while at the peak of hepatitis B infection an increase in their number was observed in the mild and moderate forms of the disease and a decrease, in the severe form of the disease. In chronic persistent hepatitis a decrease in the content of T-suppressors and an increase in the content of T-helpers were observed, and in chronic active hepatitis (at the period of remission) and increase in the T-helpers occurred. Changes in the content of the cells of both types are not characteristic of HBsAg carriership.

Translated title of the contributionCharacteristics of immune response regulation in viral hepatitis A and B
Original languageRussian
Pages (from-to)57-61
Number of pages5
JournalZhurnal Mikrobiologii Epidemiologii i Immunobiologii
Issue number8
StatePublished - Aug 1985

ASJC Scopus subject areas

  • Medicine(all)

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    Bliuger, A. F., Veksler, K. M., Osna, N. A., Charnaia, R. G., & Novitskiǐ, I. N. (1985). Osobennosti reguliatsii immunnogo otveta pri virusnykh gepatitakh A i B. Zhurnal Mikrobiologii Epidemiologii i Immunobiologii, (8), 57-61.