Characterization of methicillin-resistant Staphylococcus aureus isolated at Tripoli Medical Center, Libya, between 2008 and 2014

Elloulu BenDarif, Asma Khalil, Abdunnabi Rayes, Emad Bennour, Abdulgader Dhawi, John J. Lowe, Shawn Gibbs, Richard V. Goering

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Bacterial pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) represent a well-known public health problem affecting both healthcare-associated and community populations. Past studies have clearly shown the value of characterizing problem organisms including MRSA through the use of molecular techniques (i.e. strain typing), with the aim of informing local, regional and national efforts in epidemiological analysis and infection control. The country of Libya represents a challenge for such analysis due to limited historical infectious disease information and major political unrest culminating in the Libyan Civil War (Libyan Revolution) in 2011. A MRSA study population of 202 isolates, cultured from patients in Tripoli Medical Center through this historical period (2008-2014), was characterized by both phenotypic and molecular methods. The results revealed a diversification of epidemic MRSA strains over time with generally increasing resistance to fluoroquinolone antibiotics. The study identified prevalent MRSA in comparison to known global epidemic types, providing unique insight into the change of strains and/or characteristics over time especially with reference to the potential influence of the political revolution (i.e. pre-and post-2011).

Original languageEnglish (US)
Article number000384
Pages (from-to)1472-1475
Number of pages4
JournalJournal of Medical Microbiology
Volume65
Issue number12
DOIs
StatePublished - Dec 2016

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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