Chlorella virus PBCV-1 replication is not affected by cytoskeletal disruptors

Joseph W. Nietfeldt, Kit Lee, James L. Van Etten

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The majority, if not the entire life cycle, of the large dsDNA-containing algal virus PBCV-1 occurs in localized regions in the cytoplasm. Thirteen drugs that disrupt the cytoskeleton had no effect on PBCV-1 replication at concentrations which inhibited host growth. Therefore, host cytoskeletal elements do not appear to be important in PBCV-1 morphogenesis.

Original languageEnglish (US)
Pages (from-to)116-120
Number of pages5
Issue number2
StatePublished - 1992


  • Chlorella viruses
  • Cytoskeleton
  • PBCV-1 replication
  • Virus assembly centers

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases


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