TY - JOUR
T1 - Chromatographic immunoassays
T2 - Strategies and recent developments in the analysis of drugs and biological agents
AU - Matsuda, Ryan
AU - Rodriguez, Elliott
AU - Suresh, Doddavenkatanna
AU - Hage, David S.
N1 - Publisher Copyright:
© 2015 Future Science Ltd.
PY - 2015/11
Y1 - 2015/11
N2 - A chromatographic immunoassay is a technique in which an antibody or antibody-related agent is used as part of a chromatographic system for the isolation or measurement of a specific target. Various binding agents, detection methods, supports and assay formats have been developed for this group of methods, and applications have been reported that range from drugs, hormones and herbicides to peptides, proteins and bacteria. This review discusses the general principles and applications of chromatographic immunoassays, with an emphasis being given to methods and formats that have been developed for the analysis of drugs and biological agents. The relative advantages or limitations of each format are discussed. Recent developments and research in this field, as well as possible future directions, are also considered.
AB - A chromatographic immunoassay is a technique in which an antibody or antibody-related agent is used as part of a chromatographic system for the isolation or measurement of a specific target. Various binding agents, detection methods, supports and assay formats have been developed for this group of methods, and applications have been reported that range from drugs, hormones and herbicides to peptides, proteins and bacteria. This review discusses the general principles and applications of chromatographic immunoassays, with an emphasis being given to methods and formats that have been developed for the analysis of drugs and biological agents. The relative advantages or limitations of each format are discussed. Recent developments and research in this field, as well as possible future directions, are also considered.
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U2 - 10.4155/bio.15.206
DO - 10.4155/bio.15.206
M3 - Review article
C2 - 26571109
AN - SCOPUS:84948151638
SN - 1757-6180
VL - 7
SP - 2947
EP - 2966
JO - Bioanalysis
JF - Bioanalysis
IS - 22
ER -