Clinical and microbiologic features of children presenting with pertussis to a canadian pediatric hospital during an eleven-year period

M. Gordon, H. D. Davies, R. Gold

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

To characterize the morbidity of pertussis in Canada, we did a retrospective review of all children with laboratory-confirmed pertussis seen at the Hospital for Sick Children, Toronto, between 1980 and 1990. A total of 975 patients were identified, of which 223 (23%) were admitted to hospital. The peak incidence of disease was observed in the fall. The incidence of disease did not vary with gender. Only 41% of children admitted had the classical symptoms of pertussis (paroxysmal cough and whoop). Compared with children older than 6 months of age, children younger than 6 months of age were more likely to be hospitalized, tended to be hospitalized longer, were less likely to be age-appropriately vaccinated and were more likely to require intensive care unit monitoring. Seventeen (8%) of 223 children required intensive care unit monitoring, and 12 of these children required mechanical ventilation therapy, for a duration of 3.5 ±0.6 days (mean± SD). One (0.1%) patient with secondary bacterial pneumonia died. This hospital-based study indicates that pertussis continues to be a cause of serious illness in children, particularly those younger than 6 months of age.

Original languageEnglish (US)
Pages (from-to)617-622
Number of pages6
JournalPediatric Infectious Disease Journal
Volume13
Issue number7
DOIs
StatePublished - Jul 1994

Keywords

  • Childhood
  • Pertussis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Clinical and microbiologic features of children presenting with pertussis to a canadian pediatric hospital during an eleven-year period'. Together they form a unique fingerprint.

  • Cite this