Cloning and sequencing of the cDNA encoding human glutaredoxin

M. Rohan Fernando, Hideki Sumimoto, Hiroki Nanri, Shun ichiro Kawabata, Sadaaki Iwanaga, Shigeki Minakami, Yasuyuki Fukumaki, Koichiro Takeshige

Research output: Contribution to journalArticlepeer-review

23 Scopus citations


Glutaredoxin (thioltransferase) is a small, heat-stable protein, which is involved in thiol/disulfide exchange reactions. We have isolated a cDNA that encodes glutaredoxin from a human brain cDNA library. The encoded protein contains 106 amino acids with a calculated molecular mass of 11.76 kDa and an isoelectric point of 8.09. The amino acid sequence deduced from the cDNA is more than 80% identical to those of other mammalian glutaredoxins.

Original languageEnglish (US)
Pages (from-to)229-231
Number of pages3
JournalBBA - Gene Structure and Expression
Issue number2
StatePublished - Jun 21 1994
Externally publishedYes


  • (Human)
  • Glutaredoxin
  • Nucleotide sequence
  • Thioltransferase
  • cDNA cloning

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics


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