Cloning and sequencing of the cDNA encoding human glutaredoxin

M. Rohan Fernando, Hideki Sumimoto, Hiroki Nanri, Shun ichiro Kawabata, Sadaaki Iwanaga, Shigeki Minakami, Yasuyuki Fukumaki, Koichiro Takeshige

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Glutaredoxin (thioltransferase) is a small, heat-stable protein, which is involved in thiol/disulfide exchange reactions. We have isolated a cDNA that encodes glutaredoxin from a human brain cDNA library. The encoded protein contains 106 amino acids with a calculated molecular mass of 11.76 kDa and an isoelectric point of 8.09. The amino acid sequence deduced from the cDNA is more than 80% identical to those of other mammalian glutaredoxins.

Original languageEnglish (US)
Pages (from-to)229-231
Number of pages3
JournalBBA - Gene Structure and Expression
Volume1218
Issue number2
DOIs
Publication statusPublished - Jun 21 1994

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Keywords

  • (Human)
  • Glutaredoxin
  • Nucleotide sequence
  • Thioltransferase
  • cDNA cloning

ASJC Scopus subject areas

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

Cite this

Fernando, M. R., Sumimoto, H., Nanri, H., Kawabata, S. I., Iwanaga, S., Minakami, S., ... Takeshige, K. (1994). Cloning and sequencing of the cDNA encoding human glutaredoxin. BBA - Gene Structure and Expression, 1218(2), 229-231. https://doi.org/10.1016/0167-4781(94)90019-1