Cnidarian toxins acting on voltage-gated ion channels

Shanta M. Messerli, Robert M. Greenberg

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review cnidarian toxins known to target voltage-gated ion channels, the specific channel types targeted, and, where known, the sites of action of cnidarian toxins on different channels.

Original languageEnglish (US)
Pages (from-to)70-81
Number of pages12
JournalMarine Drugs
Volume4
Issue number3
DOIs
StatePublished - Apr 2006

Keywords

  • Cnidaria
  • Ion channels
  • Potassium channel
  • Sodium channel
  • Toxin

ASJC Scopus subject areas

  • Drug Discovery

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