Abstract
Voltage-gated ion channels generate electrical activity in excitable cells. As such, they are essential components of neuromuscular and neuronal systems, and are targeted by toxins from a wide variety of phyla, including the cnidarians. Here, we review cnidarian toxins known to target voltage-gated ion channels, the specific channel types targeted, and, where known, the sites of action of cnidarian toxins on different channels.
Original language | English (US) |
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Pages (from-to) | 70-81 |
Number of pages | 12 |
Journal | Marine Drugs |
Volume | 4 |
Issue number | 3 |
DOIs | |
State | Published - Apr 2006 |
Externally published | Yes |
Keywords
- Cnidaria
- Ion channels
- Potassium channel
- Sodium channel
- Toxin
ASJC Scopus subject areas
- Drug Discovery