TY - JOUR
T1 - Color M-Mode and Doppler Tissue Evaluation of Diastolic Function in Children
T2 - Simultaneous Correlation with Invasive Indices
AU - Border, William L.
AU - Michelfelder, Erik C.
AU - Glascock, Betty J.
AU - Witt, Sandra A.
AU - Spicer, Robert L.
AU - Beekman, Robert H.
AU - Kimball, Thomas R.
PY - 2003/9
Y1 - 2003/9
N2 - Objective: The purpose of this study was to explore the validity of diastolic indices derived from color M-mode Doppler and Doppler tissue imaging in a heterogeneous group of pediatric patients by comparing them with simultaneously obtained invasive indices of diastolic function. Methods: A total of 20 children undergoing left heart catheterization had echocardiographic images recorded simultaneously with high-fidelity left ventricular (LV) pressure tracings. Transmitral Doppler, pulmonary vein Doppler, Doppler tissue imaging, and color M-mode Doppler flow propagation velocity were recorded. LV peak negative dP/dt, the time constant of isovolumic relaxation, and LV end-diastolic pressure were compared with the echocardiographic indices. Results: The ratio of peak E-wave mitral velocity/propagation velocity correlated significantly with LV end-diastolic pressure (r = 0.71; P < .001). Propagation velocity correlated with the time constant of isovolumic relaxation (r = -0.56; P = .01) and peak negative dP/dt (r = 0.50; P < .03). Septal mitral annular myocardial velocity correlated significantly with the time constant of isovolumic relaxation (r = -0.58, P = .01). Conclusion: The newer diastolic indices derived from color M-mode Doppler and Doppler tissue imaging appear to be a helpful adjunct in the non-invasive assessment of diastolic function in children.
AB - Objective: The purpose of this study was to explore the validity of diastolic indices derived from color M-mode Doppler and Doppler tissue imaging in a heterogeneous group of pediatric patients by comparing them with simultaneously obtained invasive indices of diastolic function. Methods: A total of 20 children undergoing left heart catheterization had echocardiographic images recorded simultaneously with high-fidelity left ventricular (LV) pressure tracings. Transmitral Doppler, pulmonary vein Doppler, Doppler tissue imaging, and color M-mode Doppler flow propagation velocity were recorded. LV peak negative dP/dt, the time constant of isovolumic relaxation, and LV end-diastolic pressure were compared with the echocardiographic indices. Results: The ratio of peak E-wave mitral velocity/propagation velocity correlated significantly with LV end-diastolic pressure (r = 0.71; P < .001). Propagation velocity correlated with the time constant of isovolumic relaxation (r = -0.56; P = .01) and peak negative dP/dt (r = 0.50; P < .03). Septal mitral annular myocardial velocity correlated significantly with the time constant of isovolumic relaxation (r = -0.58, P = .01). Conclusion: The newer diastolic indices derived from color M-mode Doppler and Doppler tissue imaging appear to be a helpful adjunct in the non-invasive assessment of diastolic function in children.
UR - http://www.scopus.com/inward/record.url?scp=0242467844&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0242467844&partnerID=8YFLogxK
U2 - 10.1016/S0894-7317(03)00511-X
DO - 10.1016/S0894-7317(03)00511-X
M3 - Article
C2 - 12931112
AN - SCOPUS:0242467844
SN - 0894-7317
VL - 16
SP - 988
EP - 994
JO - Journal of the American Society of Echocardiography
JF - Journal of the American Society of Echocardiography
IS - 9
ER -