Coma in a 20-month-old child from an ingestion of a toy containing 1,4-butanediol, a precursor of γ-hydroxybutyrate

Laura A. Ortmann; Matthew W. Jaeger; Laura P. James; Steve M. Schexnayder

doi:10.1097/PEC.0b013e3181bec93b

Coma in a 20-month-old child from an ingestion of a toy containing 1,4-butanediol, a precursor of γ-hydroxybutyrate

Laura A. Ortmann, Matthew W. Jaeger, Laura P. James, Steve M. Schexnayder

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Ingestion of plastic toys is common in children and usually does not result in harm. We report a case of coma in a 20-month-old child after an ingestion of a toy containing 1,4-butanediol, an industrial solvent used to manufacture plastics. When ingested, 1,4-butanediol is metabolized to γ- hydroxybutyrate, which can have significant systemic effects including death. Health care providers should suspect the possibility of a toxic component when a presumed nontoxic object causes unusual symptoms.

Original language	English (US)
Pages (from-to)	758-760
Number of pages	3
Journal	Pediatric Emergency Care
Volume	25
Issue number	11
DOIs	https://doi.org/10.1097/PEC.0b013e3181bec93b
State	Published - Nov 2009
Externally published	Yes

Keywords

1,4-butanediol
F-hydroxybutyrate
Ingestion
Toxicology

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Emergency Medicine

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10.1097/PEC.0b013e3181bec93b

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AU - Schexnayder, Steve M.

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AB - Ingestion of plastic toys is common in children and usually does not result in harm. We report a case of coma in a 20-month-old child after an ingestion of a toy containing 1,4-butanediol, an industrial solvent used to manufacture plastics. When ingested, 1,4-butanediol is metabolized to γ- hydroxybutyrate, which can have significant systemic effects including death. Health care providers should suspect the possibility of a toxic component when a presumed nontoxic object causes unusual symptoms.

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KW - Toxicology

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Coma in a 20-month-old child from an ingestion of a toy containing 1,4-butanediol, a precursor of γ-hydroxybutyrate

Abstract

Keywords

ASJC Scopus subject areas

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