Combination anti-VEGF and corticosteroid therapy for idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome

Gagan K. Sawhney, John F. Payne, Robin Ray, Sonia Mehta, Chris S. Bergstrom, Steven Yeh

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Vision loss associated with the idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome most commonly occurs from macular edema or complications related to neovascularization. The authors present a case of advanced IRVAN associated with a massive exudative response characterized by peripheral retinal telangiectasias, exudative retinal detachment, and macular edema with lipid maculopathy. The patient was managed successfully with visual acuity from hand motion to 20/150 using a combination of local corticosteroids, intravitreal bevacizumab, panretinal photocoagulation, and eventually pars plana vitrectomy for progressive vitreomacular traction. VEGF- and non-VEGF-mediated mechanisms appear to be involved in the pathogenesis of IRVAN given the efficacy of combination therapy.

Original languageEnglish (US)
Pages (from-to)599-602
Number of pages4
JournalOphthalmic Surgery Lasers and Imaging
Volume44
Issue number6
DOIs
StatePublished - Nov 2013
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

Fingerprint

Dive into the research topics of 'Combination anti-VEGF and corticosteroid therapy for idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome'. Together they form a unique fingerprint.

Cite this