Combinations of conventional disease-modifying antirheumatic drugs

During the last decade, numerous new treatments and treatment approaches have literally transformed current thinking about rheumatoid arthritis (RA) and more, importantly, about the way patients are treated. The nearly universal acceptance of the use of combinations of disease-modifying antirheumatic drugs (DMARDs) to more effectively treat a growing percentage of patients with RA has been a central theme. Importantly controlled studies have no shown many combinations to be well tolerated and significantly more effective than mono-DMARD therapy.