Comparative Analysis of Graph and Relational Databases using HerbMicrobeDB

Suganya Chandrababu, Dhundy R. Bastola

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Network pharmacology is an emerging approach for establishing the 'compounds-proteins/genes-diseases' network, aiding in drug target prediction through the interactions between the small molecules and the host microbes. In recent years, considerable information on the biochemical properties, location and biological properties of herbal phytochemicals and their interactions with the host through the microbiome have been accumulated and made available as repositories accessible to the general public. However, the scattered data from thousands of experiments, publications and other diverse sources make the storage, retrieval, in particular, data integration process, a cumbersome task. Additionally, new knowledge about the phytochemical properties and associated functions is constantly being discovered. Such a dynamic nature and multiple integrated relationships between the elements has made it difficult to manage the information with relational model of these databases because of its rigid schema. In the present study, we explore the effectiveness of using graph database (Neo4j) to store and effectively manage phytochemical data from 24 culinary herbs and genomic data for human microbiome. The HerbMicrobeDB (HbMDB) provides a graphically intuitive solution and simplifies the complex model, estimating the impact of herbs on microorganisms and in turn on the host.

Original languageEnglish (US)
Title of host publicationProceedings - 2018 IEEE International Conference on Healthcare Informatics Workshops, ICHI-W 2018
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages19-28
Number of pages10
ISBN (Electronic)9781538667774
DOIs
StatePublished - Jul 16 2018
Event6th IEEE International Conference on Healthcare Informatics Workshops, ICHI-W 2018 - New York, United States
Duration: Jun 4 2018Jun 7 2018

Publication series

NameProceedings - 2018 IEEE International Conference on Healthcare Informatics Workshops, ICHI-W 2018

Other

Other6th IEEE International Conference on Healthcare Informatics Workshops, ICHI-W 2018
CountryUnited States
CityNew York
Period6/4/186/7/18

Keywords

  • Relational Database, Graph Database, Phytochemicals, Culinary Herbs, Heterogeneous Networks, Neo4j.

ASJC Scopus subject areas

  • Information Systems and Management
  • Health Informatics

Fingerprint Dive into the research topics of 'Comparative Analysis of Graph and Relational Databases using HerbMicrobeDB'. Together they form a unique fingerprint.

  • Cite this

    Chandrababu, S., & Bastola, D. R. (2018). Comparative Analysis of Graph and Relational Databases using HerbMicrobeDB. In Proceedings - 2018 IEEE International Conference on Healthcare Informatics Workshops, ICHI-W 2018 (pp. 19-28). [8411676] (Proceedings - 2018 IEEE International Conference on Healthcare Informatics Workshops, ICHI-W 2018). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICHI-W.2018.00010