@inproceedings{7367ec611e0e40df83378fee1fa6c1bb,
title = "Comparing biocompatibility of titanium orthopaedic implants with and without an ultra-thin coating of TiO2 by Ion beam assisted deposition",
abstract = "The evaluation of the biocompatibility of orthopaedic implants is a main factor in the validating their healing potential. Titanium (Ti) has this unique trait along with other reliable mechanical properties, which makes it a perfect choice for orthopaedic purposes. Namavar et al. employed ion beam assisted deposition (IBAD) technique to coat a thin nano-layer of titanium oxide over different surfaces in order to increase their osseointegration properties. To compare the properties of the newly engineered nano-crystalline TiO2 surface with bulk Ti, we have studied the osteoblast functions and cellular responses on these surfaces-including adhesion, growth, and mineralization-using a human osteoblast-like cell line (SAOS-2). The correlation between surface properties and cellular responses was studied using immunofluorescence techniques and alizarin red assay. The result of this study indicated that nano-engineered TiO2 surface is superior in supporting of cellular responses of bone-forming cells as compared to orthopaedic grade Ti.",
keywords = "Biocompatibility, Biomaterial, Ion beam assisted deposition, Nanostructure, Orthopaedic",
author = "R. Miralami and F. Namavar and Thiele, {G. M.} and Sharp, {J. G.} and Garvin, {K. L.}",
year = "2016",
language = "English (US)",
series = "Advanced Materials - TechConnect Briefs 2016",
publisher = "TechConnect",
pages = "43--46",
editor = "Matthew Laudon and Fiona Case and Fiona Case and Bart Romanowicz and Bart Romanowicz",
booktitle = "Biotech, Biomaterials and Biomedical - TechConnect Briefs 2016",
note = "10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 19th Annual Nanotech Conference and Expo, and the 2016 National SBIR/STTR Conference ; Conference date: 22-05-2016 Through 25-05-2016",
}