Comparing the effects of atrazine and an environmentally relevant mixture on estrogen-responsive gene expression in the northern leopard frog and the fathead minnow

Jonathan M. Ali, Lindsey A. Knight, Del L. D'Souza, Alan S. Kolok

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

In Nebraska, fish are exposed to herbicides in agricultural runoff. The study objectives were to determine 1) if fathead minnows and northern leopard frogs exposed to atrazine experience alterations in gene expression, and 2) whether these changes are elicited by a simulated herbicide mixture. Following a 7-d exposure to atrazine, female minnows were defeminized, whereas male frogs were feminized. The mixture did not elicit statistically significant effects in either species. Environ Toxicol Chem 2018;37:1182–1188.

Original languageEnglish (US)
Pages (from-to)1182-1188
Number of pages7
JournalEnvironmental Toxicology and Chemistry
Volume37
Issue number4
DOIs
StatePublished - Apr 2018

Keywords

  • Aquatic toxicology
  • Endocrine disruptor
  • Herbicide
  • Mixture
  • Pimephales promelas
  • Rana pipiens

ASJC Scopus subject areas

  • Environmental Chemistry
  • Health, Toxicology and Mutagenesis

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