TY - JOUR
T1 - Comprehensive two-dimensional gas chromatography as a boosting technology in food-omic investigations
AU - Stilo, Federico
AU - Bicchi, Carlo
AU - Reichenbach, Stephen E.
AU - Cordero, Chiara
N1 - Publisher Copyright:
© 2021 Wiley-VCH GmbH
PY - 2021/4
Y1 - 2021/4
N2 - This review focuses on the role that comprehensive two-dimensional gas chromatography can play within the investigation workflows of food-omics and related disciplines and subdisciplines, including food metabolomics, nutrimetabolomics, sensomics, and food safety. After a short introductory survey, discussing the intriguing context of system biology and integrationist approaches of investigation, the concepts of analytical dimensions and the key characteristics of comprehensive two-dimensional gas chromatography are introduced. Through a selection of relevant examples, the boosting role of comprehensive two-dimensional gas chromatography within food-omics is described, providing to the reader evidence of how comprehensive multidimensional separations based platforms have introduced new concepts and tools in the analytical measurement of complex biological samples.
AB - This review focuses on the role that comprehensive two-dimensional gas chromatography can play within the investigation workflows of food-omics and related disciplines and subdisciplines, including food metabolomics, nutrimetabolomics, sensomics, and food safety. After a short introductory survey, discussing the intriguing context of system biology and integrationist approaches of investigation, the concepts of analytical dimensions and the key characteristics of comprehensive two-dimensional gas chromatography are introduced. Through a selection of relevant examples, the boosting role of comprehensive two-dimensional gas chromatography within food-omics is described, providing to the reader evidence of how comprehensive multidimensional separations based platforms have introduced new concepts and tools in the analytical measurement of complex biological samples.
KW - comprehensive two-dimensional gas chromatography
KW - food metabolomics
KW - food safety
KW - nutrimetabolomics
KW - sensomics
UR - http://www.scopus.com/inward/record.url?scp=85102777464&partnerID=8YFLogxK
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U2 - 10.1002/jssc.202100017
DO - 10.1002/jssc.202100017
M3 - Review article
C2 - 33586333
AN - SCOPUS:85102777464
SN - 1615-9306
VL - 44
SP - 1592
EP - 1611
JO - Journal of Separation Science
JF - Journal of Separation Science
IS - 8
ER -