Contemporary evaluation and management of tall cell variant of papillary thyroid carcinoma

Sara Cartwright; Abbey Fingeret

doi:10.1097/MED.0000000000000559

Contemporary evaluation and management of tall cell variant of papillary thyroid carcinoma

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE OF REVIEW: The purpose of this review is to describe the contemporary evaluation and management of tall cell variant of papillary thyroid carcinoma with an emphasis on the clinical features. RECENT FINDINGS: Tall cell variant of papillary thyroid carcinoma is the most common aggressive subtype. Within the last few years, the diagnostic criteria for this entity have evolved. Studies have elucidated a better understanding of the clinical implications and pathophysiology of this variant. In this review, the studies presented reflect cumulative and aggregated data from metaanalyses, systematic reviews, and large database investigations utilizing the current diagnostic criteria. SUMMARY: Overall, tall cell variant of papillary thyroid carcinoma represents an aggressive subtype of well-differentiated thyroid carcinoma with more prevalent high-risk features and a poorer clinical outcome.

Original language	English (US)
Pages (from-to)	351-357
Number of pages	7
Journal	Current Opinion in Endocrinology, Diabetes and Obesity
Volume	27
Issue number	5
DOIs	https://doi.org/10.1097/MED.0000000000000559
State	Published - Oct 1 2020

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Endocrinology
Nutrition and Dietetics

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AB - PURPOSE OF REVIEW: The purpose of this review is to describe the contemporary evaluation and management of tall cell variant of papillary thyroid carcinoma with an emphasis on the clinical features. RECENT FINDINGS: Tall cell variant of papillary thyroid carcinoma is the most common aggressive subtype. Within the last few years, the diagnostic criteria for this entity have evolved. Studies have elucidated a better understanding of the clinical implications and pathophysiology of this variant. In this review, the studies presented reflect cumulative and aggregated data from metaanalyses, systematic reviews, and large database investigations utilizing the current diagnostic criteria. SUMMARY: Overall, tall cell variant of papillary thyroid carcinoma represents an aggressive subtype of well-differentiated thyroid carcinoma with more prevalent high-risk features and a poorer clinical outcome.

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Contemporary evaluation and management of tall cell variant of papillary thyroid carcinoma

Abstract

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