Continuous manufacturing of robust living fibers that withstand common textile processing for tissue engineering applications

Mohsen Akbari, Ali Tamayol, Veronique Laforte, Nasim Annabi, Ali Khademhosseini, David Juncker

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present an advanced fiber fabrication method for continuous manufacturing of composite living fibers (CLFs) with a mechanically strong core thread coated with layers of cell- or submicron bead-laden hydrogels. To demonstrate the suitability of the fabricated CFLs for textile processes, we assemble them into complex 3D structures with braiding and knitting methods. Our results indicate that the CLFs hold their mechanical integrity during the manufacturing process. Our method lays the foundation for making advanced engineered tissue constructs using textile processes.

Original languageEnglish (US)
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages1176-1178
Number of pages3
ISBN (Print)9781632666246
StatePublished - Jan 1 2013
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: Oct 27 2013Oct 31 2013

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume2

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period10/27/1310/31/13

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Keywords

  • Biotextiles
  • Cell-laden fibers
  • Fiber-based tissue engineering
  • Scaffolds

ASJC Scopus subject areas

  • Bioengineering

Cite this

Akbari, M., Tamayol, A., Laforte, V., Annabi, N., Khademhosseini, A., & Juncker, D. (2013). Continuous manufacturing of robust living fibers that withstand common textile processing for tissue engineering applications. In 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 (pp. 1176-1178). (17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013; Vol. 2). Chemical and Biological Microsystems Society.