Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: Optimizing for cyclization-trapping over cycloisomerization

James M. Takacs; Scott D. Schroeder; Jianxin Han; Meg Gifford; Xun Tian Jiang; Twana Saleh; Suresh Vayalakkada; Amy H. Yap

doi:10.1021/ol035253m

Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: Optimizing for cyclization-trapping over cycloisomerization

James M. Takacs, Scott D. Schroeder, Jianxin Han, Meg Gifford, Xun Tian Jiang, Twana Saleh, Suresh Vayalakkada, Amy H. Yap

Chemistry

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

[Equation presented] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode.

Original language	English (US)
Pages (from-to)	3595-3598
Number of pages	4
Journal	Organic Letters
Volume	5
Issue number	20
DOIs	https://doi.org/10.1021/ol035253m
State	Published - Oct 2 2003

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol035253m

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title = "Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: Optimizing for cyclization-trapping over cycloisomerization",

abstract = "[Equation presented] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode.",

author = "Takacs, {James M.} and Schroeder, {Scott D.} and Jianxin Han and Meg Gifford and Jiang, {Xun Tian} and Twana Saleh and Suresh Vayalakkada and Yap, {Amy H.}",

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T2 - Optimizing for cyclization-trapping over cycloisomerization

AU - Takacs, James M.

AU - Schroeder, Scott D.

AU - Han, Jianxin

AU - Gifford, Meg

AU - Jiang, Xun Tian

AU - Saleh, Twana

AU - Vayalakkada, Suresh

AU - Yap, Amy H.

PY - 2003/10/2

Y1 - 2003/10/2

N2 - [Equation presented] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode.

AB - [Equation presented] Screening combinations of five catalyst precursors with 13 phosphorus ligands identified cyclization catalysts that favor carbocyclization-trapping with N-hydroxyphthalimide over a competing cycloisomerization mode.

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JO - Organic Letters

JF - Organic Letters

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Controlling mode selectivity in palladium-catalyzed bisdiene carbocyclizations: Optimizing for cyclization-trapping over cycloisomerization

Abstract

ASJC Scopus subject areas

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