PURPOSE: To analyze the induced corneal higher order aberrations (HOAs) after wavefront-optimized ablation. METHODS: Sixty-four myopic eyes that underwent wavefront-optimized myopic LASIK were divided into three groups based on spherical equivalent (SE): low myopia group (23 eyes with SE <-3.00 diopters [D]); moderate myopia group (27 eyes with SE between -3.00 and -6.00 D); and high myopia group (14 eyes with SE >-6.00 D). Total corneal HOA, corneal spherical aberrations, corneal coma through a 6-mm pupil size, and corneal eccentricity were measured with a dual Scheimpfl ug imaging device preoperatively and 3 months after surgery. RESULTS: An overall increase in total corneal HOA was observed with a mean of 0.18±0.18 μm (P<.01), although this induction was not statistically signifi cant in the low myopic group with a mean of 0.006±0.15 μm (P=.85). Root-mean-square spherical aberration varied the most after myopic ablation, with an overall induction of positive spherical aberration of 0.27±0.25 μm (P<.001). CONCLUSIONS: Although the wavefront-optimized profi le was designed to preserve the preoperative HOAs of the total eye, a signifi cant induction of the corneal HOAs after myopic treatment was observed. The magnitude of the induced corneal HOA was related to the amount of intended correction. Corneal wavefront profi les do not refl ect the visual performance; however, they provide relevant information, which may help in optimizing new laser treatment algorithms.
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