Abstract
Creatine (Cr) is a compound that is synthesized endogenously in the kidneys, liver, and pancreas by the transamidination and subsequent transmethylation of three constituent amino acids: glycine, agrinine, and methionine (1). As a result of its amino acid origin, Cr can also be manufactured and consumed as a nutritional supplement. Consequently, Cr is currently regarded as a true ergogenic aid, owing to many well-controlled clinical trials that have demonstrated increases in muscle strength, power output, and muscle mass in response to exogenous Cr consumption (1-6). In fact, aside from the potential ergogenic benefits of caffeine, Cr is the most widely marketed nutritional supplement in the world.
Original language | English (US) |
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Title of host publication | Essentials of Creatine in Sports and Health |
Publisher | Humana Press |
Pages | 45-99 |
Number of pages | 55 |
ISBN (Print) | 9781588296900 |
DOIs | |
State | Published - 2008 |
Externally published | Yes |
ASJC Scopus subject areas
- General Medicine