@article{35466c1a70bd4dafbfd09a5bbc24d9f7,
title = "Cross-validation of a high-performance liquid chromatography nevirapine plasma assay in a resource-limited setting in Zimbabwe",
abstract = "An international HIV pharmacology specialty laboratory (PSL) was established at the University of Zimbabwe to increase bioanalytical and investigator capacities. Quantitation of plasma nevirapine in samples from the AIDS Clinical Trials Group protocol 5279 was compared between the University of Nebraska Medical Center PSL and the University of Zimbabwe PSL. Both PSLs employed internally developed methods utilising reverse-phase high-performance liquid chromatography with ultraviolet detection. Eighty-seven percent of the cross-validation results exhibited ± 20% difference.",
keywords = "Cross-validation, HIV, High-performance liquid chromatography, Root-cause analysis",
author = "Faithful Makita-Chingombe and Podany, {Anthony T.} and Timothy Mykris and Farai Muzambi and Browne, {Richard W.} and Ocque, {Andrew J.} and Robin DiFrancesco and Winchester, {Lee C.} and Fletcher, {Courtney V.} and Tinashe Mudzviti and Maponga, {Charles C.} and Morse, {Gene D.}",
note = "Funding Information: University of Zimbabwe IPSL: Project was funded by the United States National Institute of Allergy and Infectious Diseases, National Institutes of Health (AIDS Clinical Trials Group Grant 5UM1AI106701-04). University of Nebraska PSL: Project was funded by the United States National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services Awards ATP (K23 AI134307), and CVF (UM AI106701). Clinical Pharmacology Quality Assurance Program: This project has been funded in whole or in part with federal funds from the United States National Institute of Allergy and Infectious Diseases, National Institutes of Health and the Department of Health and Human Services, under contract numbers HHSN272201500006C and HHSN272200800019C. Center for AIDS Research: This publication was made possible through core services and support from the University of Rochester Center for AIDS Research, a United States National Institutes of Health-funded programme (P30 AI078498). Publisher Copyright: {\textcopyright} 2021. The Authors.",
year = "2021",
doi = "10.4102/AJLM.V10I1.1264",
language = "English (US)",
volume = "10",
journal = "African Journal of Laboratory Medicine",
issn = "2225-2002",
publisher = "AOSIS (Pty) Ltd",
number = "1",
}