Small cell lung cancer (SCLC) has a clinical course that is distinct from its more common counterpart non-small cell lung cancer. SCLC continues to be a major clinical problem, with an aggressive clinical course and short disease-free duration after initial therapy. Current optimal treatment consists of chemotherapy with platinum-etoposide, given concurrently with thoracic irradiation in patients with limited stage disease and chemotherapy alone in those with extensive stage. Prophylactic cranial irradiation (PCI) is recommended for patients who have responded to initial therapy, as it not only decreases the risk of brain metastases and but also improves overall survival. Newer targeted agents are currently being evaluated for this disease.

Original languageEnglish (US)
Pages (from-to)1043-1051
Number of pages9
JournalIndian Journal of Medical Research
Issue number6
StatePublished - Jun 2013


  • Cisplatin
  • Etoposide
  • Prophylactic cranial irradiation
  • Small cell lung cancer
  • Thoracic radiation

ASJC Scopus subject areas

  • General Medicine


Dive into the research topics of 'Current concepts in the management of small cell lung cancer'. Together they form a unique fingerprint.

Cite this