Cytogenetic findings in clear cell chondrosarcoma

Jun Nishio; John D. Reith; Akira Ogose; Gary Maale; James R. Neff; Julia A. Bridge

doi:10.1016/j.cancergencyto.2005.03.003

Cytogenetic findings in clear cell chondrosarcoma

Jun Nishio, John D. Reith, Akira Ogose, Gary Maale, James R. Neff, Julia A. Bridge

Pathology & Microbiology

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Clear cell chondrosarcoma is a rare cartilaginous tumor of low-grade malignancy that most often arises in the epiphysis of long bones in the third and fourth decades of life. Cytogenetic studies of clear cell chondrosarcoma are few. In this study, the cytogenetic findings of 4 cases of clear cell chondrosarcoma are presented. Clonal chromosomal abnormalities were detected in 3 cases. A tumor specific anomaly was not identified, however, extra copies of chromosome 20 and loss or rearrangements of 9p appear to be recurrent.

Original language	English (US)
Pages (from-to)	74-77
Number of pages	4
Journal	Cancer genetics and cytogenetics
Volume	162
Issue number	1
DOIs	https://doi.org/10.1016/j.cancergencyto.2005.03.003
State	Published - Oct 1 2005

ASJC Scopus subject areas

Molecular Biology
Genetics
Cancer Research

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title = "Cytogenetic findings in clear cell chondrosarcoma",

abstract = "Clear cell chondrosarcoma is a rare cartilaginous tumor of low-grade malignancy that most often arises in the epiphysis of long bones in the third and fourth decades of life. Cytogenetic studies of clear cell chondrosarcoma are few. In this study, the cytogenetic findings of 4 cases of clear cell chondrosarcoma are presented. Clonal chromosomal abnormalities were detected in 3 cases. A tumor specific anomaly was not identified, however, extra copies of chromosome 20 and loss or rearrangements of 9p appear to be recurrent.",

author = "Jun Nishio and Reith, {John D.} and Akira Ogose and Gary Maale and Neff, {James R.} and Bridge, {Julia A.}",

note = "Funding Information: This work was supported in part by the Gladys Pearson Fellowship in Pediatric Cancer and Genetics, Nebraska State Department of Health (LB595), and NIH (P30 CA 36727). The authors would like to thank Ms. Kimberly Christian for her expert secretarial assistance.",

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T1 - Cytogenetic findings in clear cell chondrosarcoma

AU - Nishio, Jun

AU - Reith, John D.

AU - Ogose, Akira

AU - Maale, Gary

AU - Neff, James R.

AU - Bridge, Julia A.

N1 - Funding Information: This work was supported in part by the Gladys Pearson Fellowship in Pediatric Cancer and Genetics, Nebraska State Department of Health (LB595), and NIH (P30 CA 36727). The authors would like to thank Ms. Kimberly Christian for her expert secretarial assistance.

PY - 2005/10/1

Y1 - 2005/10/1

N2 - Clear cell chondrosarcoma is a rare cartilaginous tumor of low-grade malignancy that most often arises in the epiphysis of long bones in the third and fourth decades of life. Cytogenetic studies of clear cell chondrosarcoma are few. In this study, the cytogenetic findings of 4 cases of clear cell chondrosarcoma are presented. Clonal chromosomal abnormalities were detected in 3 cases. A tumor specific anomaly was not identified, however, extra copies of chromosome 20 and loss or rearrangements of 9p appear to be recurrent.

AB - Clear cell chondrosarcoma is a rare cartilaginous tumor of low-grade malignancy that most often arises in the epiphysis of long bones in the third and fourth decades of life. Cytogenetic studies of clear cell chondrosarcoma are few. In this study, the cytogenetic findings of 4 cases of clear cell chondrosarcoma are presented. Clonal chromosomal abnormalities were detected in 3 cases. A tumor specific anomaly was not identified, however, extra copies of chromosome 20 and loss or rearrangements of 9p appear to be recurrent.

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Cytogenetic findings in clear cell chondrosarcoma

Abstract

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