Decoding Neuron Transcriptome by SAGE

Y. C. Kim; S. M. Wang

doi:10.1016/B978-008045046-9.00879-2

Decoding Neuron Transcriptome by SAGE

Y. C. Kim, S. M. Wang

Genetics, Cell Biology & Anatomy

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

Serial analysis of gene expression (SAGE) is a widely used technique for gene expression studies and novel gene identification. SAGE has been extensively used to analyze gene expression in the human brain, including normal brain tissue and various types of brain tumor samples. This article summarizes the SAGE data collected from the human brain. Comparison with known human transcript sequences shows that most of the known human genes are expressed in the brain tissues. Mapping SAGE tags to the human genome sequences suggests the presence of substantial unknown transcribed regions in the human genome.

Original language	English (US)
Title of host publication	Encyclopedia of Neuroscience
Publisher	Elsevier Ltd
Pages	357-363
Number of pages	7
ISBN (Print)	9780080450469
DOIs	https://doi.org/10.1016/B978-008045046-9.00879-2
State	Published - 2009

Keywords

Annotation
Brain
Brain tumor
Gene expression
Genome
LongSAGE
Mapping
Normal tissue
Novel gene
SAGE
Tag
Transcriptome

ASJC Scopus subject areas

General Neuroscience

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10.1016/B978-008045046-9.00879-2

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KW - Brain tumor

KW - Gene expression

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KW - Mapping

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KW - Tag

KW - Transcriptome

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BT - Encyclopedia of Neuroscience

PB - Elsevier Ltd

ER -

Decoding Neuron Transcriptome by SAGE

Abstract

Keywords

ASJC Scopus subject areas

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