Deep grey matter "black T2" on 3 tesla magnetic resonance imaging correlates with disability in multiple sclerosis

Y. Zhang, R. K. Zabad, X. Wei, L. M. Metz, M. D. Hill, J. Ross Mitchell

Research output: Contribution to journalArticle

42 Scopus citations


T2 hypointensity (black T2, BT2) in the deep grey matter of multiple sclerosis (MS) patients correlate weakly with disability at 1.5T. BT2 is likely to be caused by abnormal iron deposition. We compared the correlation between disability and deep grey matter BT2 measured on 3T MRI and on 1.5 T MRI in 17 MS patients. We observed a significant correlation between expanded disability status scale and signal intensity on 3 T MRI in the globus pallidus and the caudate nucleus (r = -0.5, P < 0.05). BT2 at 3 T may be a useful MRI measure associated with disability in MS and warrants further study.

Original languageEnglish (US)
Pages (from-to)880-883
Number of pages4
JournalMultiple Sclerosis
Issue number7
StatePublished - Aug 1 2007



  • Black T2
  • Deep grey matter
  • Disability
  • High field MRI
  • Iron deposition
  • Multiple sclerosis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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