Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorder

Tristan Gorrindo, R. J.R. Blair, Salima Budhani, Daniel P. Dickstein, Daniel S. Pine, Ellen Leibenluft

Research output: Contribution to journalArticlepeer-review

86 Scopus citations

Abstract

Objective: Patients with bipolar disorder become hyperhedonic when manic and anhedonic when depressed; therefore, it is important to test whether patients with bipolar disorder show deficits on behavioral paradigms exploring reward/punishment mechanisms. Method: A probabilistic response-reversal task was administered to 24 bipolar children and 25 comparison subjects. Results: Patients made more errors during probabilistic reversal, took longer to learn the new reward object, and were less likely to meet the learning criterion. Conclusions: Children with bipolar disorder may have a reversal learning deficit.

Original languageEnglish (US)
Pages (from-to)1975-1977
Number of pages3
JournalAmerican Journal of Psychiatry
Volume162
Issue number10
DOIs
StatePublished - Oct 2005

ASJC Scopus subject areas

  • Psychiatry and Mental health

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