@article{02465d66efd04a12b115ba1128e0707d,
title = "Defining cerebrospinal fluid HIV RNA escape: Editorial review AIDS",
abstract = "Suppression of plasma HIV RNA is most often attainable with effective antiretroviral therapy. Despite this, in some individuals, detection of HIV RNA remains evident in the cerebrospinal fluid (CSF) which is generally termed CSF HIV RNA escape. Defining CSF HIV RNA escape from a virological point of view, a symptomatology point of view and its management has many challenges with several different definitions being utilized. In this editorial, we outline proposed consensus definitions of CSF HIV RNA escape with consideration of virological, symptomatology and management aspects of this condition.",
keywords = "HIV RNA, central nervous system, cerebrospinal fluid, cerebrospinal fluid escape",
author = "Alan Winston and Andrea Antinori and Paola Cinque and Fox, {Howard S.} and Magnus Gisslen and Henrich, {Timothy J.} and Scott Letendre and Deborah Persaud and Price, {Richard W.} and Serena Spudich",
note = "Funding Information: We thank the National Institutes of Health/National Institute of Mental Health and specifically Drs Jeymohan Joseph and Dianne Rausch who organized and sponsored the Second Global HIV Cerebrospinal Fluid Escape Consortium. We also thank Dr Paola Cinque and the Scientific Committee of the NeuroHIV 2017 Seventh International Meeting on HIV Infection of the Central Nervous System. Ongoing studies of CSF escape by P.C., M.G., R.W.P. and S.S. are supported by NIH grant R01NS094067. A.W. is supported by the National Institute for Health Research (NIHR) Imperial Biomedical Research Centre (BRC). Publisher Copyright: Copyright {\textcopyright} 2019 Wolters Kluwer Health, Inc. All rights reserved.",
year = "2019",
month = dec,
day = "1",
doi = "10.1097/QAD.0000000000002252",
language = "English (US)",
volume = "33",
pages = "S107--S111",
journal = "AIDS",
issn = "0269-9370",
publisher = "Lippincott Williams and Wilkins",
}