Detechip®: Developing a molecular sensing device

Macduff O. Okuom, Andrea E. Holmes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Detechip® is a detection system made of various sensors that has been shown to detect and discriminate between small molecules of interest, including various illicit drugs for and over-the-counter medications, explosives, pesticides and food spoilage metabolites. Detechip® employs an array of sensors from which an analyte is tested and based on changes in color; a code specific to the analyte is developed. Detechip® offers possibilities for a simple, sensitive, selective, and affordable alternative to costly immunoassays. Results from NMR, UV-VIS and fluorimetry studies suggest that the color and fluorescence changes are a result of intermolecular interaction between the analytes and sensors ranging from non-covalent covalent bonding of supramolecular structure to proton exchange between the analyte and sensor molecules. Current efforts are focused on miniaturization of Detechip® to the micro and nanoscale.

Original languageEnglish (US)
Title of host publicationTechnical Proceedings of the 2014 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2014
PublisherNano Science and Technology Institute
Pages211-214
Number of pages4
ISBN (Print)9781482258271
StatePublished - 2014
EventNanotechnology 2014: MEMS, Fluidics, Bio Systems, Medical, Computational and Photonics - 2014 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2014 - Washington, DC, United States
Duration: Jun 15 2014Jun 18 2014

Publication series

NameTechnical Proceedings of the 2014 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2014
Volume2

Other

OtherNanotechnology 2014: MEMS, Fluidics, Bio Systems, Medical, Computational and Photonics - 2014 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2014
CountryUnited States
CityWashington, DC
Period6/15/146/18/14

Keywords

  • Colorimetric array
  • Detechip®
  • Drug detection
  • RGB Code
  • Sensor

ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials

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  • Cite this

    Okuom, M. O., & Holmes, A. E. (2014). Detechip®: Developing a molecular sensing device. In Technical Proceedings of the 2014 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2014 (pp. 211-214). (Technical Proceedings of the 2014 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2014; Vol. 2). Nano Science and Technology Institute.